Resistant isn't the same as impenetrable
Chemicals penetrate the material at a molecular level, without you noticing anything. That's why the standard works with breakthrough times: the time between first contact and the moment the substance reaches the inside. That time keeps running, even if you take the glove off and put it back on later.
Choose by substance, not by feel
Nitrile is strong against oils and many solvents, neoprene and butyl score better against acids and ketones, and PVC is economical for aqueous solutions. Look up your specific substance in the manufacturer's resistance list and check the type (A, B or C) on the glove. If you work with substances that also splash, combine with eye protection and splash-resistant coveralls.